5-Amino-1MQ
A small-molecule NNMT inhibitor that increases cellular NAD+ and β-hydroxybutyrate — investigational for metabolic health and fat-loss support.
Definition
5-Amino-1MQ is a nicotinamide-N-methyltransferase (NNMT) inhibitor — technically a small molecule rather than a peptide, but frequently stocked alongside peptides. NNMT inhibition preserves NAD+ and raises β-hydroxybutyrate, a ketone body with metabolic-signalling effects. Preclinical data is promising for fat loss, metabolic resilience and muscle preservation; human clinical data is early.
How Meto uses it.
Considered at Meto case-by-case as a research-forward adjunct for members with specific metabolic goals. Evidence base is preclinical-leaning; framed as a considered addition rather than a first-line choice.
Safety notes
- Human clinical evidence is early
- Avoid in pregnancy and lactation
- No significant drug-drug interactions documented to date
Not a complete list — your clinician reviews your full history, labs and medications during intake. Nothing here replaces that.
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NAD+Nicotinamide Adenine Dinucleotide
A co-enzyme every cell uses to make energy. Levels drop ~50% by age 60; injected NAD+ restores the baseline.
PeptideMOTS-cMitochondrial Open Reading Frame of 12S rRNA type-c
A 16-amino-acid peptide encoded in mitochondrial DNA that improves insulin sensitivity and cellular energy output.
MechanismLipolysis
The biological breakdown of stored fat into free fatty acids — the mechanism targeted by AOD-9604 and Tesamorelin.
$149 panel.
A clinician reads it in 24 hours.
Order the Peptide Readiness Panel, draw at a Quest or LabCorp near you, and your clinician sends back a matched protocol with a confidence score.