Circadian Rhythm
The body's ~24-hour biological clock that governs sleep, hormone release and cellular repair
Definition
The circadian rhythm is a roughly 24-hour cycle that orchestrates sleep-wake timing, cortisol and melatonin release, core body temperature and growth-hormone pulses. Disruption from shift work, late-night light exposure or age-related pineal decline can blunt deep sleep and recovery. Epitalon and, indirectly, the GHRH analogs (CJC-1295, Tesamorelin) restore or leverage this rhythm.
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EpitalonEpithalon
A four-amino-acid peptide that upregulates telomerase activity and restores pineal circadian signalling — typically cycled 10 days, quarterly.
MechanismGrowth HormoneGH
A pituitary-secreted hormone that drives protein synthesis, fat metabolism and tissue repair — released in pulses, peaking at night.
Clinical ConceptMelatonin
The hormone secreted by the pineal gland at night that regulates sleep-wake timing — downstream of circadian-active peptides.
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