Melatonin
The hormone secreted by the pineal gland at night that regulates sleep-wake timing — downstream of circadian-active peptides.
Definition
Melatonin is a serotonin-derived hormone secreted by the pineal gland in response to darkness, entraining the sleep-wake cycle to environmental light. Its production declines substantially with age — by age 70 nocturnal peaks can be a fraction of youthful levels. Peptides that restore pineal function (Epitalon) indirectly support melatonin rhythm; direct melatonin supplementation is a separate intervention.
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Pineal Gland
A small endocrine gland in the brain that secretes melatonin — the anatomical origin of Epitalon's developmental story.
PeptideEpitalonEpithalon
A four-amino-acid peptide that upregulates telomerase activity and restores pineal circadian signalling — typically cycled 10 days, quarterly.
Clinical ConceptCircadian Rhythm
The body's ~24-hour biological clock that governs sleep, hormone release and cellular repair
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