meto
Peptide

GHK-Cu

Also known as Copper Tripeptide-1 · Copper Peptide

A naturally occurring copper-binding tripeptide that activates tissue-repair gene programs and collagen synthesis — used topically and injected.

Definition

GHK-Cu (glycyl-histidyl-lysine complexed with copper) is a three-amino-acid peptide that decreases with age. It modulates expression of roughly four thousand human genes associated with tissue repair, inflammation and extracellular-matrix remodelling. Clinical applications include skin quality, wound healing, post-procedure recovery and systemic connective-tissue support, with activity via both topical and subcutaneous routes.

How Meto uses it.

GHK-Cu appears in the RENEW recovery stack. Dosing includes topical serum at 0.1–2% daily, or subcutaneous injection at 1–3 mg daily for 4–8 week cycles, with many members combining both approaches.

Safety notes

  • Contraindicated in Wilson's disease and other copper-metabolism disorders
  • Avoid in active malignancy
  • Avoid in pregnancy and lactation
  • Topical form is well-tolerated; rare contact dermatitis reported

Not a complete list — your clinician reviews your full history, labs and medications during intake. Nothing here replaces that.

Common questions

Topical vs. injected GHK-Cu — which should I choose?

Topical works where it touches — skin quality, hair follicle support, post-procedure recovery at a specific site. Injected reaches systemic tissues including connective, pulmonary and vascular.

Will it help with hair regrowth?

There's reasonable evidence for follicle support and perifollicular inflammation reduction, especially in early-stage androgenetic alopecia.

Does the copper get absorbed systemically?

Yes, at the injected doses used, with copper status remaining within normal range across an 8-week cycle for typical members.

$149 panel.
A clinician reads it in 24 hours.

Order the Peptide Readiness Panel, draw at a Quest or LabCorp near you, and your clinician sends back a matched protocol with a confidence score.