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Biomarker

Homocysteine

An amino-acid metabolite — elevated values indicate B-vitamin deficiency and are an independent cardiovascular risk marker.

Definition

Homocysteine is a methionine metabolite whose levels rise with deficiencies in B12, folate or B6, and with impaired methylation (MTHFR variants). Elevated homocysteine is an independent cardiovascular and cognitive-decline risk marker; correction is straightforward with methylated B-vitamin replacement, though whether that translates to reduced events is contested.

$149 panel.
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Order the Peptide Readiness Panel, draw at a Quest or LabCorp near you, and your clinician sends back a matched protocol with a confidence score.