Hormones & Metabolism

How Cortisol Affects Blood Sugar and Insulin Resistance (And What to Do About It)

By Karyn O.

Reviewed by Kenya Bass, PA-C

Published May 26, 2025

8 min read

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Have you ever noticed that your energy crashes after a stressful day, or that you crave sugar and carbs when you're overwhelmed? That’s not just in your head—it’s actually rooted in how your body responds to stress. The key player here is a hormone called cortisol, and it has a surprisingly powerful effect on your blood sugar and how your body processes insulin.

Most of us think of stress as an emotional or mental state. But stress triggers physical reactions in your body too. One of the biggest is how your blood sugar levels respond when cortisol, your main stress hormone, gets involved. Over time, if cortisol levels stay high, this can lead to something called insulin resistance. That’s when your body doesn’t respond to insulin properly, which can set you up for weight gain, fatigue, and even type 2 diabetes.

This article will walk you through what cortisol is, how it affects your blood sugar, why insulin resistance happens, and what you can do to stay in balance. Whether you're feeling burned out or just curious about how stress affects your health, you're in the right place.

What Is Cortisol? Your Body’s Main Stress Hormone

Cortisol is a hormone made by your adrenal glands—small glands that sit on top of your kidneys. It’s often called the “stress hormone” because your body releases more of it when you're under pressure, in danger, or even just running late for work.

But cortisol isn’t a bad thing. In fact, it plays a lot of important roles. It helps your body wake up in the morning, keeps your blood pressure in check, controls inflammation, and even helps regulate your metabolism.

Cortisol follows a natural rhythm throughout the day. It usually peaks in the early morning to help you wake up and feel alert. Then it gradually decreases as the day goes on, reaching its lowest point at night to help you fall asleep.

The real trouble starts when your cortisol levels stay too high for too long—something that can happen if you're constantly stressed, not sleeping enough, or even over-exercising.

Cortisol’s Role in Blood Sugar Regulation

Cortisol has a direct effect on your blood sugar levels. When your body senses danger or stress, it prepares you to either fight or flee. This is often called the “fight or flight” response. In order to give you the energy you need to take action, cortisol signals your liver to release glucose (a type of sugar) into your bloodstream.

This sugar rush gives your muscles quick energy. At the same time, cortisol makes your cells less responsive to insulin. Insulin is the hormone that normally helps move sugar from your blood into your cells. But during stress, your body wants to keep sugar in the bloodstream, where it can be used quickly.

In short bursts, this system works great. Think of it like a turbo boost when you need it. But when you’re stressed all the time, that constant sugar release and reduced insulin sensitivity can cause problems.

Chronic Stress and Cortisol Overload: What Goes Wrong

A woman feeling very stressed out

Now imagine this: your body is constantly in fight-or-flight mode. It doesn’t know the difference between being chased by a bear and being stuck in traffic, dealing with financial stress, or facing relationship drama. All of these can trigger the same stress response.

When your body is exposed to stress day after day, your cortisol levels can stay elevated. This means your liver keeps pumping out glucose, and your cells continue to ignore insulin’s signals.

Over time, your blood sugar stays high more often. Your pancreas, which makes insulin, starts working overtime to try to get that sugar into your cells. Eventually, your cells stop responding well to insulin. That’s insulin resistance.

Insulin resistance is a warning sign that your body is struggling to manage blood sugar. Left unchecked, it can lead to prediabetes or type 2 diabetes, not to mention weight gain and chronic fatigue.

How High Cortisol Leads to Insulin Resistance

To really understand this, it helps to look at what insulin resistance actually means. Insulin is like a key that unlocks your cells so sugar can get inside and be used for energy. But when cortisol is high all the time, your cells start to ignore that key. It’s like the locks on your cells get rusty.

This means sugar stays in your blood longer, and your pancreas has to make more insulin to try to get the job done. The more insulin your body pumps out, the more resistant your cells can become. It's a vicious cycle.

High cortisol can also cause fat to build up around your belly. This kind of fat isn’t just sitting there; it actually produces its own hormones and inflammation, which further contribute to insulin resistance.

Add in poor sleep, processed foods, and a lack of exercise, and your body becomes a breeding ground for blood sugar problems.

Signs You Might Be Dealing with High Cortisol and Blood Sugar Imbalance

You might be wondering: how do I know if this is happening to me?

While blood tests are the best way to know for sure, your body often gives you warning signs. If you’re dealing with high cortisol and insulin resistance, you might notice:

  • You crave sugar or salty snacks often
  • You're gaining weight around your midsection, even if your diet hasn't changed
  • You feel tired, but also wired and anxious
  • Your sleep is poor, and you often wake up in the middle of the night
  • You feel like you need caffeine to function

These symptoms can be your body’s way of saying that your cortisol and blood sugar systems are out of balance. If this sounds like you, it might be time to start making changes.

How to Lower Cortisol Naturally (and Improve Insulin Sensitivity)

The good news is that you don’t have to be stuck in a cortisol-blood sugar loop forever. Your body is incredibly resilient and can heal with the right support.

One of the most powerful tools is managing your stress in ways that don’t involve ignoring it or just pushing through. Simple lifestyle changes can help bring cortisol levels down naturally.

Getting enough sleep is one of the most underrated strategies. Aim for 7 to 9 hours a night and try to stick to a consistent sleep schedule. Sleep resets your cortisol rhythm and helps your body respond better to insulin.

A person practicing mindfulness to reduce stress

Mindfulness practices like deep breathing, meditation, or even a few minutes of quiet time can lower cortisol levels. So can spending time in nature or connecting with people you care about.

Exercise is also a great tool, but it’s important to strike a balance. Overtraining or doing high-intensity workouts every day can actually raise cortisol. Instead, mix in strength training, walking, yoga, or light cardio to keep your stress hormones in check.

Lastly, your mindset matters. Chronic stress isn’t always about what’s happening—it’s about how your body and brain are reacting. Building resilience and emotional regulation can go a long way in lowering your stress load.

Best Foods to Balance Cortisol, Blood Sugar, and Insulin

Food plays a huge role in keeping cortisol and blood sugar balanced. Some foods help stabilize energy, while others can trigger spikes and crashes.

Focus on whole, unprocessed foods that are rich in fiber, protein, and healthy fats. These help keep your blood sugar steady and prevent the roller coaster that keeps cortisol active.

Magnesium-rich foods like leafy greens, nuts, seeds, and legumes can help your body manage stress and support insulin sensitivity.

Avoiding processed sugars, refined carbs, and caffeine overload is also key. These can trigger cortisol spikes and cause your blood sugar to crash shortly after, keeping you in that cycle of highs and lows.

If you’re hungry for something sweet, try pairing it with protein or fat to slow down the blood sugar response. For example, a banana with almond butter is a better option than a cookie on its own.

RELATED READ: Ultimate Low Glycemic Foods List: A Science-Backed Guide for Better Health

FAQs: Cortisol, Insulin Resistance, and Stress

1. Can stress alone cause insulin resistance?

Chronic stress can be a major factor. While diet and exercise are important, your stress response system plays a big role in how your body handles blood sugar.

2. How do I know if cortisol is affecting my blood sugar?

If you’re feeling anxious, tired but wired, gaining belly fat, or craving sugar often, it could be a sign. Blood tests can measure cortisol and insulin levels to give you a clearer picture.

3. Are there tests for cortisol or insulin resistance?

Yes. You can ask your doctor for tests like fasting insulin, fasting glucose, A1C, or even a cortisol saliva test to check your levels throughout the day.

Absolutely. With changes to your sleep, stress management, exercise, and diet, many people are able to improve insulin sensitivity and reduce cortisol levels naturally.

Final Thoughts: Don’t Let Stress Control Your Blood Sugar

Your body is built to handle stress, but only in small bursts. When that stress becomes chronic, and cortisol stays high, it can throw your entire metabolism off balance. Over time, that can lead to insulin resistance, weight gain, fatigue, and even chronic diseases.

But here’s the empowering truth: you have more control than you think. By making small, daily changes—like getting better sleep, eating real food, moving your body, and learning to manage stress—you can bring your cortisol levels back into balance and support healthy blood sugar.

Stress is part of life. But it doesn’t have to run your life. When you understand how cortisol works, you can work with your body instead of against it. And that’s the first step toward lasting energy, balanced metabolism, and better health overall.

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