
Lose Weight with Phentermine-Topiramate
Phentermine-Topiramate is a prescription weight loss medication that combines an appetite suppressant (Phentermine) with a medication that affects brain signals related to hunger (Topiramate). Together, they help reduce appetite, increase feelings of fullness, and support long-term weight management.
- Balances blood sugar
- Same active ingredient in Wegovy® and Ozempic®.
- Personalized weight loss plans from meto’s licensed experts
Everything you need to know about Injectable compounded Phentermine-Topiramate

What is Phentermine-Topiramate
Phentermine-topiramate is a combination medication that includes phentermine, an appetite suppressant, and topiramate, which can help reduce appetite.
It is used for weight management in adults with obesity or overweight who have weight-related medical problems.
Phentermine-topiramate is taken along with a reduced-calorie diet and increased physical activity to promote weight loss.
Is Phentermine-Topiramate Safe and Effective for Weight Loss?
Phentermine-topiramate is generally safe when used appropriately. However, close monitoring is crucial. Patients should report any adverse effects promptly.
In terms of effectiveness, clinical trials demonstrate significant weight loss when combined with lifestyle modifications. Patients typically lose around 5-10% of their initial body weight within the first year. Individual responses vary, but consistent adherence yields better outcomes. Our healthcare team emphasizes the importance of long-term commitment to achieve sustained results.

How Does the Phentermine-Topiramate Work?
Phentermine primarily acts by suppressing appetite through its effect on the central nervous system, reducing feelings of hunger. It stimulates the release of norepinephrine, a neurotransmitter that helps control appetite.
Topiramate has various effects on neurotransmitters and brain activity. It enhances the activity of GABA, an inhibitory neurotransmitter that can reduce overeating, and it modulates the activity of glutamate, a neurotransmitter involved in appetite regulation. The combination of these effects helps to decrease food intake and increase feelings of fullness.
The cost of Phentermine-Topiramate can vary depending on factors such as insurance coverage, dosage strength, and quantity prescribed. Brand name Qsymia can be relatively expensive, with an estimated cost of up to $200 for a 30-day supply. However, generic versions of phentermine and topiramate may be more affordable, generally ranging from $30 to $60 for a 30-day supply.