
Sermorelin for Weight Loss
Sermorelin is a peptide that stimulates the body’s natural production of growth hormone, supporting energy, recovery, fat loss, and healthy aging.
- Balances blood sugar
- Same active ingredient in Wegovy® and Ozempic®.
- Personalized weight loss plans from meto’s licensed experts
Everything you need to know about Injectable compounded Sermorelin

What is Sermorelin
Sermorelin is a synthetic fragment of growth-hormone-releasing hormone (GHRH). By nudging your pituitary gland to release pulses of natural growth hormone (GH), it helps the body burn fat, preserve lean muscle, improve sleep quality, and enhance overall recovery. When paired with a balanced diet and regular exercise, many adults report gradual fat-mass reduction—often five percent or more within six to twelve months—along with steadier energy and a stronger sense of well-being.
Is Sermorelin safe and effective for weight loss?
Adult case series and clinical programs show consistent reductions in visceral and subcutaneous fat, modest gains in lean muscle, and better sleep architecture over six to twelve months of nightly therapy.
Average fat-mass loss of five to seven percent is common when injections are combined with calorie control and regular physical activity. Results vary with baseline pituitary health:
Adults whose GH output has simply declined with age often respond more robustly than those with longstanding pituitary impairment.

How does Sermorelin work?
After a subcutaneous injection, Sermorelin binds to GHRH receptors on somatotroph cells in the anterior pituitary. This triggers a cyclic-AMP cascade and a burst of endogenous GH release.
Pulsatile secretion maintains normal feedback control by somatostatin, reducing the risk of overstimulation and helping preserve the body’s day-night hormone rhythm.
Higher GH and downstream IGF-1 levels promote lipolysis, protein synthesis, bone remodeling, and deeper restorative sleep—key drivers of improved body composition and recovery.
Because Sermorelin is compounded rather than mass-produced, pricing differs by pharmacy and concentration. A typical 30-day supply of multi-dose vials (3 mg – 6 mg total peptide) falls in the $120 – $250 range. Needed supplies—bacteriostatic water, insulin syringes, and sharps disposal—add only a few extra dollars per month, while many wellness clinics bundle medication, supplies, and routine IGF-1 blood tests into a single subscription fee.