Restore Thyroid Balance with Natural Desiccated Thyroid (NDT)
Natural Desiccated Thyroid (NDT) is a hormone replacement therapy made from dried animal thyroid glands, typically porcine (pig). It provides both T3 and T4 thyroid hormones to help treat hypothyroidism—supporting energy, metabolism, and overall hormonal balance.
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Everything you need to know about Injectable compounded Natural Desiccated Thyroid
What is Natural Desiccated Thyroid
Natural Desiccated Thyroid—sometimes called “thyroid extract” or simply “desiccated thyroid”—is a prescription hormone replacement made from purified, dried porcine thyroid glands. Because it supplies both thyroxine (T4) and triiodothyronine (T3) in proportions similar to what a healthy human thyroid releases, NDT can normalize thyroid-hormone levels more comprehensively than T4-only therapy. Many patients report steadier energy, warmer body temperature, clearer thinking, healthier hair and skin, and overall hormonal equilibrium after switching to or starting NDT.
NDT has been part of endocrine care since the late 1800s. Modern brands—such as Armour Thyroid®, Nature-Throid®, and NP Thyroid®—are carefully purified, assayed, and standardized for potency. Each “grain” (65 mg of dried powder) contains roughly 38 µg of T4 and 9 µg of T3, plus trace amounts of T2, T1, and calcitonin. Compounding pharmacies can also prepare hypoallergenic, slow-release capsules tailored to any strength.
Is NDT safe and effective?
For patients with primary hypothyroidism—or those who remain symptomatic on T4 monotherapy—individualized NDT dosing can restore laboratory values and relieve classic low-thyroid symptoms within four to eight weeks. Many people notice improvements in mood, cognitive sharpness, circulation (warmer hands and feet), menstrual regularity, and lipid profiles
As with any thyroid therapy, clinical benefits depend on correct dosing and regular follow-up to keep hormone levels within physiologic limits.
How does NDT work?
After you swallow the tablet on an empty stomach, the T3 fraction begins acting within hours, supporting cellular energy and nervous-system function. The T4 fraction converts gradually to additional T3 in the liver and other tissues, providing sustained coverage through the day.
his dual-hormone profile more closely mimics normal thyroid physiology than levothyroxine alone, which must rely entirely on peripheral conversion.
Pricing varies by brand and location, but a month’s supply of 60 mg tablets typically runs between $20 and $40 at major U.S. pharmacies. Insurance plans that cover levothyroxine often reimburse NDT, though some may require prior authorization. Custom compounded capsules cost more yet remain affordable, especially when ordered in 90-day quantities.
