How to Safely Get Off Metformin: A Step-by-Step Guide Backed by Science
By Karyn O.
Reviewed by Dr. Jossy Onwude
Published Apr 19, 2025
9 min read

Metformin is one of the most commonly prescribed medications for type 2 diabetes, and for good reason — it’s effective, affordable, and generally well tolerated. But what happens if you feel like it’s time to stop taking it? Maybe your blood sugar levels are under control. Maybe you’ve made major lifestyle changes like eating healthier, exercising regularly, and losing weight. Or maybe you’re dealing with side effects and wondering if there’s a better option for you.
Whatever your reason, you're not alone in asking: How do I get off Metformin?
Before you decide to stop taking Metformin, it’s important to understand how it works, why it's prescribed, and the safest way to make a change. In this article, we’ll walk you through everything you need to know — in simple, clear language — so you can make an informed decision with the support of your healthcare provider.
Let’s dive in.
What Is Metformin and Why Is It Prescribed?
Metformin is a medication that helps lower blood sugar. It’s most often used to treat type 2 diabetes, a condition where your body doesn’t use insulin properly (also called insulin resistance). When your body resists insulin, sugar builds up in your bloodstream, which can lead to serious health problems if not managed.
Metformin works by:
- Reducing how much sugar your liver makes,
- Helping your muscles use sugar more effectively, and
- Making your body more sensitive to insulin.
It doesn’t work like insulin injections — it doesn’t force sugar out of your blood. Instead, it gently nudges your body to improve how it manages blood sugar on its own.
Doctors also prescribe Metformin for conditions like polycystic ovary syndrome (PCOS), prediabetes, or weight gain caused by certain medications. It’s usually taken as a pill once or twice a day, and in many cases, it’s the first medicine doctors try for blood sugar control.
Why Do People Want to Stop Taking Metformin?

Even though Metformin has helped millions of people, it’s not perfect for everyone. Some people experience side effects like nausea, bloating, gas, or diarrhea, especially when they first start taking it. Others feel tired or weak, possibly because Metformin can reduce levels of vitamin B12 over time.
But side effects aren’t the only reason people want to stop. In many cases, the motivation is positive — people feel better and healthier, and wonder if they still need to be on medication.
Here are a few common reasons people ask about stopping Metformin:
- They’ve lost weight and improved their diet and exercise habits.
- Their blood sugar levels have stayed in a healthy range for months or years.
- They want to explore natural or non-drug approaches to managing their condition.
- They’re switching to a different medication.
And of course, some people just want to take fewer pills.
Can You Just Stop Taking Metformin?
The short answer? No, you shouldn’t stop taking Metformin on your own. Even if you’re feeling great or your blood sugar is under control, it’s important to talk to your doctor before making any changes.
Why? Because suddenly stopping Metformin can cause your blood sugar to rise, sometimes without you even noticing at first. This can put you at risk for serious health problems like nerve damage, vision loss, or heart disease.
Plus, blood sugar levels can be tricky. They may look good for a few weeks, but then start to climb again if you stop taking your meds. That’s why most doctors recommend a gradual, step-by-step approach.
Think of it like this: You wouldn’t quit a workout plan cold turkey if you were training for a marathon. You’d slowly reduce the intensity and keep checking your progress. Getting off Metformin is no different — it takes time, patience, and a plan.
How to Safely Get Off Metformin: Step-by-Step
If you’re serious about stopping Metformin, here’s how to do it the right way — safely and with support.
Step 1: Talk to Your Doctor
This might seem obvious, but it’s the most important step. Your doctor can help you understand whether you’re truly ready to stop Metformin, based on your current health, blood sugar readings, and lifestyle habits.
They might run a few tests, like A1C (a 3-month average of your blood sugar), fasting glucose, or even check your vitamin B12 levels. This gives a clearer picture of how well your body is handling blood sugar without relying on medication.
Step 2: Monitor Your Blood Sugar Closely
Once your doctor agrees that it might be time to reduce your dose, you’ll need to keep an eye on your blood sugar — ideally every day, especially in the morning before you eat (called fasting blood sugar).
Regular monitoring helps you catch any issues early. If your blood sugar starts creeping up, you can make adjustments before things get out of control.
If you don’t already have a blood glucose monitor, now is the time to get one. Your doctor or pharmacist can help you pick one that’s easy to use.
Step 3: Improve (or Maintain) Your Diet and Exercise Routine
Here’s where the real magic happens. Lifestyle changes are the foundation of long-term blood sugar control. Medications like Metformin help, but they don’t replace good habits.
If you’re thinking about getting off Metformin, you’ll want to focus on:
- Eating plenty of fiber-rich foods (like veggies, beans, and whole grains),
- Limiting sugary drinks and processed carbs,
- Moving your body every day — even a 30-minute walk can make a difference.
You don’t have to become a gym rat or go on a strict diet. Small, consistent changes are more effective than big, unsustainable ones.
Step 4: Reduce Your Dose Gradually
This step must be done with your doctor’s guidance. They might suggest cutting your daily dose in half, skipping every other day, or switching to a lower-dose version of the drug.
The goal is to see how your body responds to a lower amount of Metformin before stopping completely. It might take a few weeks or even a few months — and that’s okay. Going slowly gives your body time to adjust and reduces the chance of blood sugar spikes.
Step 5: Keep Tracking Your Progress
As your dose decreases, you’ll need to stay on top of how you feel, how your blood sugar looks, and any changes in your energy, mood, or digestion. These are all clues your body is giving you.
Your doctor will probably want to check in with you regularly and may run a few more blood tests along the way.
Step 6: Celebrate Your Success — Whatever That Looks Like
If you’re able to come off Metformin completely, that’s great! But even if you end up staying on a lower dose, that’s still progress. The goal isn’t to get off meds at all costs — the goal is to be healthy, balanced, and in control of your condition.
What to Expect When You Stop Taking Metformin

When you stop taking Metformin, you might notice a few changes in your body, and not all of them are bad.
Some people feel less bloated or notice improved digestion. Others feel more energized, especially if Metformin was lowering their vitamin B12 levels.
But here’s the key: You need to stay alert for any signs that your blood sugar is rising. This might include:
- Feeling unusually thirsty,
- Peeing more often than usual,
- Feeling tired or foggy,
- Blurry vision, or
- Cuts and bruises that take longer to heal.
If any of these show up, check your blood sugar and call your doctor. It doesn’t mean you’ve failed — it just means your body might need more time or support.
Lifestyle Changes That Support Getting Off Metformin
If you’re looking for long-term success, it’s not just about stopping the pill — it’s about building a lifestyle that keeps your blood sugar steady on its own.
Here are a few habits that can make a big difference:
Diet
Choose foods that don’t spike your blood sugar. This means more vegetables, whole grains, legumes, lean proteins, and healthy fats. You don’t have to cut out all carbs, but try to limit added sugars and highly processed foods.
Exercise
Physical activity helps your muscles use sugar more effectively, even hours after your workout. Aim for at least 150 minutes of moderate activity each week — like walking, biking, or swimming.
Weight Management
Losing even 5-10% of your body weight (if you’re overweight) can dramatically improve blood sugar levels and insulin sensitivity.
Sleep & Stress
Lack of sleep and chronic stress can both increase blood sugar. Try to get at least 7–8 hours of sleep each night and find healthy ways to unwind, whether that’s reading, stretching, or talking to a friend.
Who Should NOT Stop Taking Metformin?
Some people really do need Metformin, even if they’re living a healthy lifestyle. You should not stop taking it if:
- Your blood sugar is still high without it,
- You’ve had serious diabetes-related complications (like kidney problems or heart disease),
- You haven’t made consistent changes to your diet and activity levels.
In these cases, Metformin is often the safest and most effective option, and there’s no shame in that.
What Are the Alternatives to Metformin?

If Metformin isn’t working for you or causes side effects, there are other options. Your doctor might recommend:
- SGLT2 inhibitors (like Jardiance or Farxiga), which help your body get rid of sugar through your urine,
- GLP-1 receptor agonists (like Ozempic), which help your body make more insulin and slow down digestion,
- Natural supplements like berberine (sometimes called “nature’s Metformin”), although more research is needed.
Keep in mind that even natural alternatives can have side effects or interact with other medications, so always check with your healthcare provider before trying something new.
Final Thoughts: It’s About Progress, Not Perfection
Getting off Metformin isn’t a competition or a badge of honor. It’s a personal health decision that should be based on facts, not fear, and definitely not guilt.
For some people, staying on Metformin is the best way to stay healthy. For others, stopping it is a realistic goal after months or years of lifestyle improvements.
What matters most is that you feel empowered, informed, and supported every step of the way.
If you're ready to explore this journey, talk to your doctor. Ask questions. Monitor your body. And most importantly, give yourself credit for how far you’ve come.
Frequently Asked Questions (FAQ)
1. Can I stop Metformin cold turkey?
It’s not recommended. Stopping suddenly can lead to blood sugar spikes. It’s safer to taper down slowly with medical supervision.
2. What happens to my blood sugar if I stop Metformin?
Your blood sugar may rise, especially if your lifestyle hasn’t changed. That’s why monitoring is key during this process.
3. Can supplements replace Metformin?
Some supplements like berberine, may help lower blood sugar, but they’re not a substitute for medical treatment. Always check with your doctor first.
4. Does stopping Metformin mean I’m cured?
No, but it may mean your condition is well-managed without medication. You’ll still need to monitor your health and stick to your healthy habits.
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