Meto vs. Second Nature: Which Metabolic Health Platform is Right for You?

Second Nature is a digital health program designed to help users lose weight primarily through behavioral changes and lifestyle adjustments. The platform emphasizes healthier habits like mindful eating, exercise, sleep improvement, and stress management. Users receive guidance from qualified dietitians and health coaches through digital tools and group support. Second Nature is centered around lifestyle education, behavior modification, and habit formation without relying on restrictive diets or calorie counting, appealing to those seeking sustainable, gradual weight loss.

Meto, on the other hand, is a doctor-led metabolic health platform focused on addressing underlying physiological and hormonal factors contributing to weight gain and metabolic dysfunction. Unlike Second Nature, Meto goes beyond lifestyle changes alone and integrates medical care, prescription management (including GLP-1 medications such as Mounjaro), personalized lab tests, and AI-driven health insights. Designed particularly for individuals dealing with metabolic health challenges like PCOS, insulin resistance, or hormonal imbalances, Meto provides comprehensive, clinically supervised care. Additionally, Meto’s services are insurance-compatible, enhancing accessibility to medically robust, long-term care.

Features	Meto	Second Nature
Approach to Care	Medical-led, personalized metabolic and hormonal health care.	Behavior-focused lifestyle coaching and habit formation.
Use of Technology	AI-powered clinical insights, telehealth, integrated device/lab data (CGMs, wearables).	App-based behavior tracking, digital habit-building tools, and educational content.
Insurance Coverage	Accepts most major insurance providers.	Typically not insurance-covered; subscription-based service.
Pricing Model	Copay (insurance-eligible), transparent medical subscription model.	Monthly subscription with optional premium coaching services.
Clinical Team Availability	Licensed physicians, nurse practitioners, metabolic health specialists, dietitians, and health coaches.	Registered dietitians and certified health coaches (non-medical clinicians).
Availability	Currently U.S.-focused, expanding nationally.	Primarily available in the UK and Australia; limited U.S. presence.
Program Flexibility	Highly personalized, adaptable medical and wellness plans tailored to metabolic profiles.	General behavior-change program adaptable to individual preferences.
Patient Support	Dedicated medical care team providing ongoing, personalized consultations and care.	Coach-led digital group support, with optional one-on-one coaching.
Mobile & Web Experience	Comprehensive mobile and web app with clinical dashboards, advanced monitoring, and telehealth integration.	Robust mobile and web apps focused on behavior tracking and education.
Community and Peer Support	Provider-supported community with clinical expertise and educational events.	Strong peer-support community via app-based groups and forums.

Second Nature operates on the philosophy that lasting weight loss and improved health are achieved primarily through sustainable lifestyle and behavior changes. Instead of calorie counting or restrictive diets, Second Nature prioritizes building healthier habits around nutrition, physical activity, sleep, and stress management. Members benefit from structured educational content, support from health coaches, and the accountability provided by group engagement. This habit-based framework attracts users seeking to gradually and sustainably reshape their lifestyle rather than quick or dramatic weight-loss solutions.

In contrast, Meto views weight management through a medical and metabolic lens, recognizing weight as influenced by deep physiological factors—like insulin sensitivity, hormonal fluctuations, and metabolic disorders—not just behavior. Meto employs medical diagnostics, personalized care plans, prescription medications when appropriate, and regular physician consultations. Rather than relying on willpower alone, Meto focuses on restoring metabolic health, addressing hormonal imbalances, and providing the ongoing medical supervision necessary for long-term success.

Second Nature provides evidence-based guidance primarily through registered dietitians and certified health coaches, focusing on lifestyle factors and habit formation. The platform does not offer direct medical supervision or prescription medication support, emphasizing a non-clinical, behavior-first approach. Second Nature is particularly suited for users without significant medical conditions who want structured yet flexible coaching to facilitate lasting lifestyle changes.

In contrast, Meto was explicitly designed as a comprehensive medical solution. The entire program revolves around clinical oversight from licensed physicians, nurse practitioners, and metabolic specialists. Meto providers utilize advanced lab testing, continuous health monitoring via wearables and CGMs, and prescription management—including GLP-1 medication—to manage metabolic conditions effectively. This integrated clinical approach ensures continuous medical guidance, personalized treatment plans, and support tailored to complex metabolic health needs.

Personalization in Second Nature revolves primarily around individualized behavioral coaching. Users engage with coaches who help them adapt general lifestyle guidelines to their preferences, challenges, and goals. While behavior adjustments are personalized, Second Nature does not integrate deep biological or medical factors like insulin sensitivity or hormonal imbalances into its personalization approach. This makes it best suited for users whose primary goal is lifestyle optimization rather than medical treatment or hormonal health management.

Meto, by contrast, prioritizes deep, clinical personalization. Upon enrollment, each patient undergoes comprehensive metabolic assessments, hormonal evaluations, and thorough medical intake processes. Meto’s medical team customizes each patient’s care plan based on these results, incorporating targeted treatments, nutrition strategies, and medication when needed. Continuous biometric monitoring and regular medical consultations enable ongoing adjustments, ensuring care evolves precisely with the patient’s physiological response and long-term health trajectory.

Second Nature does not offer prescription medications such as GLP-1 receptor agonists. Its model explicitly focuses on lifestyle-driven change without pharmacological interventions. As a result, Second Nature is best matched with individuals who either do not qualify for or prefer to avoid prescription medications, focusing solely on non-medical strategies for managing weight and health.

On the other hand, Meto integrates prescription medication, particularly GLP-1 medications (such as semaglutide or tirzepatide), directly into its treatment approach. Rather than viewing medication as a standalone solution, Meto embeds prescriptions into comprehensive, medically guided care plans. The clinical team actively manages medication dosing, monitors responses, provides nutritional guidance, and gradually helps patients taper off medications when possible, once sustainable metabolic health improvements have been achieved.

Choosing the ideal weight loss program depends on your health goals, the complexity of your medical needs, and your preferred approach to health management. Second Nature is an excellent fit if your primary objective is long-term lifestyle improvement through sustainable habits and general behavioral coaching. If you’re generally healthy and looking for structured guidance to support gradual, consistent change without medical intervention, Second Nature is well-positioned to help.

Conversely, Meto is ideal for individuals who require medical expertise to address deeper metabolic, hormonal, or complex health issues impacting weight. If you’ve experienced difficulty losing weight due to underlying conditions (e.g., PCOS, insulin resistance, menopause), or if lifestyle changes alone haven’t worked sustainably, Meto offers the comprehensive medical supervision, prescription support, and personalized metabolic treatment needed for lasting success.