AMPK
Also known as AMP-Activated Protein Kinase
The cellular energy sensor that triggers fat burning, glucose uptake and mitochondrial biogenesis when ATP runs low — activated by MOTS-c.
Definition
AMP-activated protein kinase is a heterotrimeric enzyme that senses the ratio of AMP to ATP in the cell and switches metabolism to energy-producing pathways when ATP is low. It increases fatty-acid oxidation, glucose uptake and mitochondrial biogenesis. MOTS-c is one of the clearest peptide activators; metformin and exercise are two of the most common non-peptide activators.
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MOTS-cMitochondrial Open Reading Frame of 12S rRNA type-c
A 16-amino-acid peptide encoded in mitochondrial DNA that improves insulin sensitivity and cellular energy output.
Clinical ConceptMitochondria
The cellular organelles that produce ATP — the direct target of NAD+ supplementation and mitochondrial peptides like MOTS-c.
MechanismLipolysis
The biological breakdown of stored fat into free fatty acids — the mechanism targeted by AOD-9604 and Tesamorelin.
$149 panel.
A clinician reads it in 24 hours.
Order the Peptide Readiness Panel, draw at a Quest or LabCorp near you, and your clinician sends back a matched protocol with a confidence score.