GLP-1 Receptor Agonist
Also known as GLP-1 RA · GLP-1 Agonist
A peptide drug class that mimics glucagon-like peptide-1 to slow gastric emptying, sharpen insulin response and quiet food-noise.
Definition
GLP-1 is released by gut cells after meals. These synthetic peptides (semaglutide, tirzepatide, liraglutide) slow gastric emptying, enhance glucose-dependent insulin secretion, reduce glucagon, and act centrally to reduce appetite and food-reward signalling. GI side effects typically emerge during dose titration and respond to BPC-157 adjunct therapy.
How Meto uses it.
Compounded semaglutide or tirzepatide via 503A pharmacy, weekly subcutaneous dosing with titration every four weeks, plus clinician-reviewed labs every 12 weeks and weekly coaching initially.
Safety notes
- Contraindicated in personal/family history of medullary thyroid cancer or MEN 2
- Contraindicated in active pancreatitis
- Avoid in pregnancy and lactation
- Rapid weight loss risks muscle loss—requires resistance training and adequate protein
- GI side effects peak during titration, typically subside afterward
Not a complete list — your clinician reviews your full history, labs and medications during intake. Nothing here replaces that.
Common questions
Compounded vs. brand formulations, insurance coverage, weight regain after discontinuation, and muscle preservation strategies
Protein 1.2–1.6 g/kg/day plus twice-weekly resistance training is recommended to preserve muscle.
Read More
SemaglutideOzempic
A long-acting GLP-1 receptor agonist used for type-2 diabetes and chronic weight management — the active ingredient in Ozempic and Wegovy.
PeptideTirzepatideMounjaro
A dual GLP-1 and GIP receptor agonist — the most effective FDA-approved weight-management peptide to date, the active ingredient in Mounjaro and Zepbound.
MechanismGastric Emptying
The rate at which food exits the stomach — slowed by GLP-1 receptor agonists, which extends satiety but can also cause nausea.
$149 panel.
A clinician reads it in 24 hours.
Order the Peptide Readiness Panel, draw at a Quest or LabCorp near you, and your clinician sends back a matched protocol with a confidence score.